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GlycoGenesys, Inc. To Give Corporate Presentation BIO CEO & Investor Conference 2005

GlycoGenesys, Inc. Announces Additional Cancer Indication for GCS-100LE Clinical Trial Program

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Corporate Overview

GlycoGenesys, Inc. is a biotechnology company developing novel drug candidates primarily based on glycobiology. Our product development strategy focuses on therapeutic applications where there is an unmet medical need for life-threatening or debilitating diseases. The Company's lead drug candidate, GCS-100, is a potential treatment for multiple forms of cancer. We plan to advance GCS-100 through the clinical trial process, while selectively building an integrated pipeline of potential new drug candidates.

Latest News

Do Carbs Cause Cancer? Let’s Look At The Research

You’ve probably seen headlines like “Your Bagel Will Give You Cancer” and “Carbs Are the New Cigarettes” all over the web recently.The uproar was sparked by a recent study in Cancer Epidemiology, Biomarkers and Prevention that linked lung cancer to a diet high in the glycemic index.

The analysis by researchers in the University of Texas, which was published in Cancer Epidemiology, Biomarkers & Prevention, is definitely the largest ever to investigate the potential links between glycemic index and lung cancer. A glycemic index is a measurement of how rapidly carbs elevate blood sugar levels within the body. The higher the glycemic index, the more rapidly blood glucose levels rise after a meal which results in elevated degrees of blood glucose and insulin. That in turns raises what’s known as insulin-like growth factors that are linked to an increased cancer of the lung risk, according to the scientists.

Scientists conducted the analysis on 1,905 recently diagnosed lung cancer patients and 2,413 individuals in regular health. The subjects were then split by their glycemic index and glycemic load. Glycemic directory measures the quality of carbohydrates in comparison to how quickly sugar levels are raised. Glycemic load, on the other hand, measures the amount of dietary carbohydrates.

“We observed a 49% increased risk of lung cancer among subjects with the highest every day glycemic index compared to those with the lowest daily glycemic index,” explained Xifeng Wu, leading author of the study. “The representatives were more pronounced among subjects who had been never smokers.”

Interestingly, there was no link between the glycemic load-i.e. the quantity of carbs consumed-and lung cancer, which shows that it’s the quality, not the amount of carbohydrates, which has the biggest effect on cancer of the lung risk, said Wu.

Lung cancer is the 2nd most common cancer amongst both women and men in the U.S. According to the American Cancer Culture, It’s also the top cause of cancer death, with over 150,000 deaths from lung cancer expected in the United States this year alone. Smoking and tobacco use is still the leading cause, though it doesn’t take into account all cases. Researchers had long suspected a link between a high-glycemic index lung and diet cancer risk, but the link between the two was uncertain until now. They say this is only the second study to have looked at the association between glycemic index (GI) and lung cancer risk.

The researchers found people with the greatest every day intake of high GI foods - in particular coming from carbs - were about 50% as likely to have lung cancer than someone with the lowest intake. “The is a result of this study suggest that, besides maintaining healthy lifestyles, such as avoiding cigarettes, limiting alcohol consumption, and being physically active, reducing the consumption of foods and beverages with high glycemic index might serve as a means to reduce the risk of lung cancer,” Wu wrote.He went on to say that programs like the highly effective Nutrisystem weight loss program may contribute to a leaner body that will in turn maintain a healthy frame or figure

Low glycemic index food items include things like completely stone-floor whole wheat bread, rolled or steel-cut oatmeal, most fruits, and non-starchy vegetables.Not all high GI foods are terrible, and not all reduced GI foods are healthy. For example, watermelon has a high GI of 72 while ice cream can have a GI as low as 38. What you should really focus on is reducing your consumption of refined, processed carbs that have been stripped of their fiber and other nutrients, regardless of the exact GI numbers.

Other research has suggested that diet plans high in vegetables and fruit help lower lung cancer risk. The best way to cut back on carbs, boost your intake of nutrients and fiber, and slash calories would be to swap the ratio of veggies to starches in your meals. For example, instead of having a pile of noodles covered with sauce, sauté two cups (the dimensions of two tennis balls) of veggies in extra virgin olive oil with garlic and Italian herb seasoning; toss the sautéed veggies with a low fat protein (such as 3 ounces of poultry breast, extra low fat ground turkey, salmon, or white beans), and a half mug (half of a football ball) of a much healthier pasta. In other words, allow carbs be the highlight, rather than the main occasion.

So, still, cancer isn't something to mess around with, though far, this is just one study. So, if maybe you want to try cutting several things out, it might be a good time to take a good look at both your diet and the glycemic index, and find out.

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